Spata19^tm1Lij
Targeted Allele Detail

Summary

• Symbol: Spata19^tm1Lij
• Name: spermatogenesis associated 19; targeted mutation 1, Jian Li
• MGI ID: MGI:6510019
• Synonyms: Spata19^flox
• Gene: Spata19 Location: Chr9:27308103-27313007 bp, + strand Genetic Position: Chr9, 12.9 cM
• Alliance: Spata19^tm1Lij page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301706
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and a lox site and neo cassette were inserted downstream of exon 4 via homologous recombination. (J:301706)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spata19 Mutation: 10 strains or lines available

References

• Original: J:301706 Mi Y, et al., Spata19 is critical for sperm mitochondrial function and male fertility. Mol Reprod Dev. 2015 Nov;82(11):907-13
• All: 1 reference(s)