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Apold1tm1Pfw
Targeted Allele Detail
Summary
Symbol: Apold1tm1Pfw
Name: apolipoprotein L domain containing 1; targeted mutation 1, Paul Worley
MGI ID: MGI:6511000
Synonyms: Verge KO
Gene: Apold1  Location: Chr6:134958964-134963799 bp, + strand  Genetic Position: Chr6, 65.77 cM
Alliance: Apold1tm1Pfw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:302897
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe open reading frame was replaced with a beta-gal/neo cassette. Western blot analysis confirmed the absence of protein expression in the brain of homozygous mutant mice. (J:302852, J:302897)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Apold1 Mutation:  22 strains or lines available
References
Original:  J:302897 Liu F, et al., Loss of vascular early response gene reduces edema formation after experimental stroke. Exp Transl Stroke Med. 2012 Jun 8;4(1):12
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory