Agtrap^tm1Tamk
Targeted Allele Detail

Summary

• Symbol: Agtrap^tm1Tamk
• Name: angiotensin II, type I receptor-associated protein; targeted mutation 1, Kouichi Tamura
• MGI ID: MGI:6511094
• Gene: Agtrap Location: Chr4:148161518-148172488 bp, - strand Genetic Position: Chr4, 78.67 cM, cytoband E1
• Alliance: Agtrap^tm1Tamk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263253
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A genomic region including exons 3 5 was replaced with a neo cassette via homologous recombination. (J:263253)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Agtrap Mutation: 127 strains or lines available

References

• Original: J:263253 Maeda A, et al., Angiotensin receptor-binding protein ATRAP/Agtrap inhibits metabolic dysfunction with visceral obesity. J Am Heart Assoc. 2013 Jul 31;2(4):e000312
• All: 6 reference(s)