Armc12^em2Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Armc12^em2Osb
• Name: armadillo repeat containing 12; endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6512490
• Synonyms: Armc12^{em2(Armc12/FLAG)Osb}
• Gene: Armc12 Location: Chr17:28749835-28757949 bp, + strand Genetic Position: Chr17, 14.74 cM
• Alliance: Armc12^em2Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:302631
• Parent Cell Line: EGR-G01 (ES Cell)
• Strain of Origin: (129S2/SvPas x C57BL/6NSlc)F1-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• CRISPR-targeting inserted a FLAG epitope tag near the stop codon. (J:302631)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Armc12 Mutation: 24 strains or lines available

References

• Original: J:302631 Shimada K, et al., ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2018355118
• All: 1 reference(s)