Armc12^em3Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Armc12^em3Osb
• Name: armadillo repeat containing 12; endonuclease-mediated mutation 3, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6512491
• Synonyms: Armc12^LD
• Gene: Armc12 Location: Chr17:28749835-28757949 bp, + strand Genetic Position: Chr17, 14.74 cM
• Alliance: Armc12^em3Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 8,015 nucleotides that encode amino acids 11 to 340. (J:302631)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Armc12 Mutation: 24 strains or lines available

References

• Original: J:302631 Shimada K, et al., ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2018355118
• All: 1 reference(s)