Del(13)1N
Spontaneous Allele Detail

Summary

• Symbol: Del(13)1N
• Name: Deletion, Chr 13, NIH 1
• MGI ID: MGI:6514360
• Gene: Del(13)1N Location: unknown Genetic Position: Chr13, Syntenic

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Spontaneous (Modified regulatory region)
• Mutation: Deletion
• Mutation details: This multigenic deletion, present in C57BL/6NJ and C57BL/6NTac but not C57BL/6J inbred strains, is approximately 1 Mb in size and spans from Chr13:65.66Mb-66.67Mb which includes several lincRNA and pseudogenes along with Zfp998 and Zfp997, with the distal breakpoint falling between Zfp997 and Zfp640. (J:282526)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Del(13)1N Mutation: 1 strain or line available

References

• Original: J:282526 Treger RS, et al., The Lupus Susceptibility Locus Sgp3 Encodes the Suppressor of Endogenous Retrovirus Expression SNERV. Immunity. 2019 Feb 19;50(2):334-347.e9
• All: 7 reference(s)