Nlrp9b^em2Okkm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nlrp9b^em2Okkm
• Name: NLR family, pyrin domain containing 9B; endonuclease-mediated mutation 2, Tohru Kimura
• MGI ID: MGI:6514377
• Synonyms: Nlrpb^delta7nt
• Gene: Nlrp9b Location: Chr7:19725318-19796867 bp, + strand Genetic Position: Chr7, 9.96 cM
• Alliance: Nlrp9b^em2Okkm page

Mutation origin

• Strain of Origin: ICR

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 3, which encodes the NACHT domain, resulted in a 7 nucleotide deletion. (J:302234)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nlrp9b Mutation: 51 strains or lines available

References

• Original: J:302234 Kanzaki S, et al., Involvement of Nlrp9a/b/c in mouse preimplantation development. Reproduction. 2020 Aug;160(2):181-191
• All: 1 reference(s)