Aqp5^{em1(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Aqp5^{em1(cre/ERT2)Smoc}
• Name: aquaporin 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6514762
• Synonyms: Aqp5^{em1(2A-CreERT2-Wpre-pA)Smoc}
• Gene: Aqp5 Location: Chr15:99488909-99492710 bp, + strand Genetic Position: Chr15, 56.13 cM
• Alliance: Aqp5^{em1(cre/ERT2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Aqp5^{em1(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Aqp5 (MGI:106215)

• Mutation details: 2A-CreERT2-Wpre-pA expression cassette was knocked into the Aqp5 gene stop codon site via CRISPR/Cas9 mediated recombination. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Aqp5 (mouse) Summary of all recombinase alleles driven by Aqp5. Alliance mouse Aqp5 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aqp5 Mutation: 19 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)