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C9em1Sjlg
Endonuclease-mediated Allele Detail
Summary
Symbol: C9em1Sjlg
Name: complement component 9; endonuclease-mediated mutation 1, Shujuan Liang
MGI ID: MGI:6514830
Gene: C9  Location: Chr15:6474808-6528232 bp, + strand  Genetic Position: Chr15, 2.79 cM, cytoband A1
Alliance: C9em1Sjlg page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsTALEN-targeting of exon 1 deleted 34 bp. Western blot analysis confirmed the absence of protein expression in the serum and liver. (J:301607)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any C9 Mutation:  45 strains or lines available
References
Original:  J:301607 Fu X, et al., Target deletion of complement component 9 attenuates antibody-mediated hemolysis and lipopolysaccharide (LPS)-induced acute shock in mice. Sci Rep. 2016 Jul 22;6:30239
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory