1700102P08Rik^em1Feis
Endonuclease-mediated Allele Detail

Summary

• Symbol: 1700102P08Rik^em1Feis
• Name: RIKEN cDNA 1700102P08 gene; endonuclease-mediated mutation 1, Fei Sun
• MGI ID: MGI:6514855
• Gene: 1700102P08Rik Location: Chr9:108270023-108275416 bp, + strand Genetic Position: Chr9, 59.3 cM
• Alliance: 1700102P08Rik^em1Feis page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of exon 2 deleted 101 bp resulting in a frame shift and premature termination. Western blot analysis confirmed the absence of protein expression. (J:301139)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any 1700102P08Rik Mutation: 18 strains or lines available

References

• Original: J:301139 Wu XL, et al., The testis-specific gene 1700102P08Rik is essential for male fertility. Mol Reprod Dev. 2020 Feb;87(2):231-240
• All: 1 reference(s)