Pirt^{tm1(cre/ERT2)Smoc}
Targeted Allele Detail

Summary

• Symbol: Pirt^{tm1(cre/ERT2)Smoc}
• Name: phosphoinositide-interacting regulator of transient receptor potential channels; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6681811
• Synonyms: Pirt^{tm1(2A-CreERT2)Smoc}
• Gene: Pirt Location: Chr11:66802807-66820702 bp, + strand Genetic Position: Chr11, 40.59 cM
• Alliance: Pirt^{tm1(cre/ERT2)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Pirt^{tm1(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pirt (MGI:2443635)

• A 2A-CreERT2 expression cassette was knocked into the Pirt gene stop codon site via ESC targeting. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pirt (mouse) Summary of all recombinase alleles driven by Pirt. Alliance mouse Pirt gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pirt Mutation: 13 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)