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Lmbrd1tm1.1Bvs
Targeted Allele Detail
Summary
Symbol: Lmbrd1tm1.1Bvs
Name: LMBR1 domain containing 1; targeted mutation 1.1, Boris V Skryabin
MGI ID: MGI:6682025
Gene: Lmbrd1  Location: Chr1:24717711-24805382 bp, + strand  Genetic Position: Chr1, 10.18 cM
Alliance: Lmbrd1tm1.1Bvs page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:302463
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  (129/Sv x C57BL/6J)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette with a 5 prime loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 3. Cre-mediated recombination removed exon 3 and the selection cassette. (J:302463)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 14 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lmbrd1 Mutation:  39 strains or lines available
Notes
ES cells = CV19 (129/Sv x C57BL/6J)F1
References
Original:  J:302463 Buers I, et al., Lmbrd1 expression is essential for the initiation of gastrulation. J Cell Mol Med. 2016 Aug;20(8):1523-33
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory