Fitm1^tm1Nani
Targeted Allele Detail

Summary

• Symbol: Fitm1^tm1Nani
• Name: fat storage-inducing transmembrane protein 1; targeted mutation 1, Natsumi Nishihama
• MGI ID: MGI:6690472
• Synonyms: Fitm1^-
• Gene: Fitm1 Location: Chr14:55813131-55814409 bp, + strand Genetic Position: Chr14, 28.19 cM
• Alliance: Fitm1^tm1Nani page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:303195
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• The entire 2-exon gene was replaced with a neomycin resistance gene cassette. (J:303195)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fitm1 Mutation: 12 strains or lines available

References

• Original: J:303195 Nishihama N, et al., Mice lacking fat storage-inducing transmembrane protein 2 show improved profiles upon pressure overload-induced heart failure. Heliyon. 2019 Mar;5(3):e01292
• All: 1 reference(s)