Bud23^em1Asil
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bud23^em1Asil
• Name: BUD23, rRNA methyltransferase and ribosome maturation factor; endonuclease-mediated mutation 1, Andrew Loudon
• MGI ID: MGI:6690826
• Synonyms: Bud23^null
• Gene: Bud23 Location: Chr5:135081811-135093813 bp, - strand Genetic Position: Chr5, 74.97 cM
• Alliance: Bud23^em1Asil page

Mutation origin

• Strain of Origin: B6D2F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to generate a deletion of exon 7. (J:290738)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bud23 Mutation: 24 strains or lines available

References

• Original: J:290738 Baxter M, et al., Cardiac mitochondrial function depends on BUD23 mediated ribosome programming. Elife. 2020 Jan 15;9:e50705
• All: 1 reference(s)