Dock11^tm1.1Mmar
Targeted Allele Detail

Summary

• Symbol: Dock11^tm1.1Mmar
• Name: dedicator of cytokinesis 11; targeted mutation 1.1, Mitsuo Maruyama
• MGI ID: MGI:6690850
• Gene: Dock11 Location: ChrX:35152485-35340215 bp, + strand Genetic Position: ChrX, 20.35 cM
• Alliance: Dock11^tm1.1Mmar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238172
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was flanked by loxP sites and deleted through subsequent cre-mediated recombination. Lack of peptide expression from this allele in lung, spleen, thymus and mesenteric lymph nodes was confirmed by Western blot experiments. (J:238172)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dock11 Mutation: 15 strains or lines available

References

• Original: J:238172 Matsuda T, et al., The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation. Immun Ageing. 2015;12:1
• All: 1 reference(s)