Nemp1^em1Hmc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nemp1^em1Hmc
• Name: nuclear envelope integral membrane protein 1; endonuclease-mediated mutation 1, Helen McNeill
• MGI ID: MGI:6693344
• Synonyms: Nemp1^{em#(TCP)McNeill}
• Gene: Nemp1 Location: Chr10:127512934-127536918 bp, + strand Genetic Position: Chr10, 74.6 cM
• Alliance: Nemp1^em1Hmc page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 3. (J:303621)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nemp1 Mutation: 36 strains or lines available

References

• Original: J:303621 Tsatskis Y, et al., The NEMP family supports metazoan fertility and nuclear envelope stiffness. Sci Adv. 2020;6(35):eabb4591
• All: 2 reference(s)