Tmem63b^em2Yss
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmem63b^em2Yss
• Name: transmembrane protein 63b; endonuclease-mediated mutation 2, Yun Stone Shi
• MGI ID: MGI:6693365
• Synonyms: Tmem63b^HA-fl
• Gene: Tmem63b Location: Chr17:45971102-45997212 bp, - strand Genetic Position: Chr17, 22.59 cM
• Alliance: Tmem63b^em2Yss page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Epitope tag)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted into intron 1 and intron 4 and hemagglutinin (HA) and FLAG tags were inserted after the N-terminal signal sequence in exon 2 via CRISPR/Cas9-mediated genome editing technology. (J:303483)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem63b Mutation: 47 strains or lines available

References

• Original: J:303483 Du H, et al., The Cation Channel TMEM63B Is an Osmosensor Required for Hearing. Cell Rep. 2020 May 5;31(5):107596
• All: 2 reference(s)