Pou4f3^{em1(cre/ERT2)Yss}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pou4f3^{em1(cre/ERT2)Yss}
• Name: POU domain, class 4, transcription factor 3; endonuclease-mediated mutation 1, Yun Stone Shi
• MGI ID: MGI:6693366
• Synonyms: Pou4f3^EGFP-CreER
• Gene: Pou4f3 Location: Chr18:42527662-42529158 bp, + strand Genetic Position: Chr18, 22.58 cM, cytoband B3-E1
• Alliance: Pou4f3^{em1(cre/ERT2)Yss} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Pou4f3^{em1(cre/ERT2)Yss} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pou4f3 (MGI:102523)

• Mutation details: An EGFP-IRES-CreER cassette was integrated at the first ATG codon of the gene via CRISPR/Cas9-mediated genome editing technology. (J:303483)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pou4f3 (mouse) Summary of all recombinase alleles driven by Pou4f3. Comparative matrix view of recombinase activities Alliance mouse Pou4f3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pou4f3 Mutation: 25 strains or lines available

References

• Original: J:303483 Du H, et al., The Cation Channel TMEM63B Is an Osmosensor Required for Hearing. Cell Rep. 2020 May 5;31(5):107596
• All: 1 reference(s)