Laidx^em1.1Jbmu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Laidx^em1.1Jbmu
• Name: large amplified intrinsically disordered protein-coding gene on the X Chromosome; endonuclease-mediated mutation 1.1, Jacob Mueller
• MGI ID: MGI:6693758
• Gene: Laidx Location: unknown Genetic Position: ChrX, Syntenic
• Alliance: Laidx^em1.1Jbmu page

Mutation origin

• Strain of Origin: (DBA/2J x C57BL/6J)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR-targeting inserted loxP sites to flank the region. Cre-mediated recombination removed the region. (J:289981)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Laidx Mutation: 2 strains or lines available

References

• Original: J:289981 Arlt MF, et al., Genomic Structure, Evolutionary Origins, and Reproductive Function of a Large Amplified Intrinsically Disordered Protein-Coding Gene on the X Chromosome (Laidx) in Mice. G3 (Bethesda). 2020 Jun 1;10(6):1997-2005
• All: 1 reference(s)