4833411C07Rik^em1Cecad
Endonuclease-mediated Allele Detail

Summary

• Symbol: 4833411C07Rik^em1Cecad
• Name: RIKEN cDNA 4833411C07 gene; endonuclease-mediated mutation 1, CECAD, University of Cologne
• MGI ID: MGI:6694243
• Synonyms: LincIRS2^em1Cecad
• Gene: 4833411C07Rik Location: Chr8:10949922-10952334 bp, + strand Genetic Position: Chr8, 5.28 cM
• Alliance: 4833411C07Rik^em1Cecad page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 mediated recombination created a 426 bp deletion (chr8:10,899,86110,900,279; GRCm38/mm10) and a 5 bp (GTCCG) insertion in a region including part of the promoter, all of exon 1, and part of exon 2. (J:285483)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any 4833411C07Rik Mutation: 0 strains or lines available

References

• Original: J:285483 Pradas-Juni M, et al., A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. Nat Commun. 2020 Jan 31;11(1):644
• All: 1 reference(s)