Cabs1^em1Ntu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cabs1^em1Ntu
• Name: calcium binding protein, spermatid specific 1; endonuclease-mediated mutation 1, Comparative Medicine Research Center of Nantong University
• MGI ID: MGI:6694874
• Gene: Cabs1 Location: Chr5:88127310-88129400 bp, + strand Genetic Position: Chr5, 43.56 cM, cytoband E2
• Alliance: Cabs1^em1Ntu page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 1 deleted most of the exon resulting in a frame shift. (J:304106)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cabs1 Mutation: 20 strains or lines available

References

• Original: J:304106 Zhang X, et al., Cabs1 Maintains Structural Integrity of Mouse Sperm Flagella during Epididymal Transit of Sperm. Int J Mol Sci. 2021 Jan 11;22(2):652
• All: 1 reference(s)