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Myh3tm1.1Sajm
Targeted Allele Detail
Summary
Symbol: Myh3tm1.1Sajm
Name: myosin, heavy polypeptide 3, skeletal muscle, embryonic; targeted mutation 1.1, Sam J Mathew
MGI ID: MGI:6695298
Synonyms: Myh3fl3-7
Gene: Myh3  Location: Chr11:66969126-66993112 bp, + strand  Genetic Position: Chr11, 40.59 cM
Alliance: Myh3tm1.1Sajm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:287755
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted into intron 2 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 7. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with exons 3-7 floxed. (J:287755)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myh3 Mutation:  74 strains or lines available
References
Original:  J:287755 Agarwal M, et al., Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory