Pdap1^em1Rkuhn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pdap1^em1Rkuhn
• Name: PDGFA associated protein 1; endonuclease-mediated mutation 1, Ralf Kuhn
• MGI ID: MGI:6695800
• Synonyms: Pdap1^F
• Gene: Pdap1 Location: Chr5:145065580-145076835 bp, - strand Genetic Position: Chr5, 85.04 cM
• Alliance: Pdap1^em1Rkuhn page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 genome editing technology was used to insert LoxP sites that flank exon 2 (ENSMUST00000031627.8). (J:298705)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdap1 Mutation: 15 strains or lines available

References

• Original: J:298705 Delgado-Benito V, et al., PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification. J Exp Med. 2020 Oct 5;217(10)
• All: 1 reference(s)