Stk26^tm1.1Zzh
Targeted Allele Detail

Summary

• Symbol: Stk26^tm1.1Zzh
• Name: serine/threonine kinase 26; targeted mutation 1.1, Zhaocai Zhou
• MGI ID: MGI:6695865
• Synonyms: Mst4^fl, Mst4^floxed, Stk26^floxed
• Gene: Stk26 Location: ChrX:49930052-49981980 bp, + strand Genetic Position: ChrX, 27.5 cM, cytoband A3.3
• Alliance: Stk26^tm1.1Zzh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:289548
• Parent Cell Line: E14K (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 8 and an FRT-flanked neomycin resistance gene cassette and a second loxP site were inserted downstream of exon 8. Flp-mediated recombination removed the neo cassette leaving exon 8 floxed. (J:289548)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stk26 Mutation: 15 strains or lines available

References

• Original: J:289548 An L, et al., MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway. J Exp Med. 2020 Jun 1;217(6)
• All: 2 reference(s)