Selenoi^em1.1Prh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Selenoi^em1.1Prh
• Name: selenoprotein I; endonuclease-mediated mutation 1.1, Peter R Hoffmann
• MGI ID: MGI:6695989
• Synonyms: SELENOI^-
• Gene: Selenoi Location: Chr5:30437579-30477425 bp, + strand Genetic Position: Chr5, 16.22 cM, cytoband B1
• Alliance: Selenoi^em1.1Prh page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were flanked by loxP sites using CRISPR/Cas9 technology. Cre-mediated recombination deleted exons 2 and 3. (J:296764)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Selenoi Mutation: 16 strains or lines available

References

• Original: J:296764 Avery JC, et al., Selenoprotein I is essential for murine embryogenesis. Arch Biochem Biophys. 2020 Aug 15;689:108444
• All: 1 reference(s)