Tg(H2-L^d)LoxNibl
Transgene Detail

Summary

• Symbol: Tg(H2-L^d)LoxNibl
• Name: transgene insertion Lox, Nicolas Blanchard
• MGI ID: MGI:6696066
• Synonyms: L^dLox
• Transgene: Tg(H2-L^d)LoxNibl Location: unknown
• Alliance: Tg(H2-L^d)LoxNibl page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Tg(H2-L^d)LoxNibl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	H2-L (MGI:95912)	H2-L gene from BALB/c with loxP sites upstream and in intron 3

• Mutation details: The transgenic construct contains the following elements: a loxP site, exons 1-3 of the BALB/c (d haplotype) derived H2-L gene, a second loxP site, and the remaining five exons. The two loxP sites are different to ensure an irreversible recombination event in the presence of cre. (J:284394)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:284394 Salvioni A, et al., Robust Control of a Brain-Persisting Parasite through MHC I Presentation by Infected Neurons. Cell Rep. 2019 Jun 11;27(11):3254-3268.e8
• All: 1 reference(s)