Dcst1^em1Nino
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dcst1^em1Nino
• Name: DC-STAMP domain containing 1; endonuclease-mediated mutation 1, Naokazu Inoue
• MGI ID: MGI:6696421
• Gene: Dcst1 Location: Chr3:89257526-89272560 bp, - strand Genetic Position: Chr3, 39.08 cM, cytoband F2
• Alliance: Dcst1^em1Nino page

Mutation origin

• Strain of Origin: C57BL/6 x DBA/2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 5 bp (GATCC). (J:304712)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dcst1 Mutation: 39 strains or lines available

References

• Original: J:304712 Inoue N, et al., Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion. Elife. 2021 Apr 19;10:e66313
• All: 1 reference(s)