Caskin2^tm1.1Lasb
Targeted Allele Detail

Summary

• Symbol: Caskin2^tm1.1Lasb
• Name: CASK-interacting protein 2; targeted mutation 1.1, Laszlo Buday
• MGI ID: MGI:6711392
• Synonyms: Caskin2^-
• Gene: Caskin2 Location: Chr11:115690009-115704465 bp, - strand Genetic Position: Chr11, 80.91 cM
• Alliance: Caskin2^tm1.1Lasb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:297862
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site and an FRT site flanked neomycin resistance gene cassette were inserted into intron 2 and a second loxP site into intron 7. Exons 3-7 and the neo cassette were deleted through subsequent cre-mediated recombination. (J:297862)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Caskin2 Mutation: 38 strains or lines available

References

• Original: J:297862 Bencsik N, et al., Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins. Sci Rep. 2019 Nov 14;9(1):16843
• All: 1 reference(s)