Lcn8^em1Jgao
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lcn8^em1Jgao
• Name: lipocalin 8; endonuclease-mediated mutation 1, Jiangang Gao
• MGI ID: MGI:6711616
• Gene: Lcn8 Location: Chr2:25543132-25546229 bp, + strand Genetic Position: Chr2, 17.67 cM, cytoband A3
• Alliance: Lcn8^em1Jgao page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 and 3 deleted 1061 bp. (J:305282)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lcn8 Mutation: 9 strains or lines available

References

• Original: J:305282 Wen Z, et al., Deficiency for Lcn8 causes epididymal sperm maturation defects in mice. Biochem Biophys Res Commun. 2021 Apr 9;548:7-13
• All: 1 reference(s)