Efhd1^em1Wei
Endonuclease-mediated Allele Detail

Summary

• Symbol: Efhd1^em1Wei
• Name: EF hand domain containing 1; endonuclease-mediated mutation 1, Weizmann Institute of Science
• MGI ID: MGI:6711681
• Gene: Efhd1 Location: Chr1:87192085-87238561 bp, + strand Genetic Position: Chr1, 44.15 cM
• Alliance: Efhd1^em1Wei page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of the promoter and exon 1 produced a null allele. Western blot analysis confirmed the absence of protein expression in dorsal root ganglia. (J:305107)

Expression

In Mice Carrying this Mutation:

15 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Efhd1 Mutation: 20 strains or lines available

References

• Original: J:305107 Ulisse V, et al., Regulation of axonal morphogenesis by the mitochondrial protein Efhd1. Life Sci Alliance. 2020 Jul;3(7)
• All: 1 reference(s)