Zfp467^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Zfp467^{tm1.1(KOMP)Vlcg}
• Name: zinc finger protein 467; targeted mutation 1.1, Velocigene
• MGI ID: MGI:6711762
• Gene: Zfp467 Location: Chr6:48404631-48422759 bp, - strand Genetic Position: Chr6, 23.39 cM
• Alliance: Zfp467^{tm1.1(KOMP)Vlcg} page
• IMPC: Zfp467 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:302865
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 15756bp between positions 48404621-48420376 of Chromosome 6 (Build GRCm39). The ZEN-Ub1 cassette contains a lacZ reporter gene cassette and loxP site flanked neomycin resistance gene cassette. The neomycin resistance gene was removed via cre-mediated recombination. (J:302865)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp467 Mutation: 22 strains or lines available

References

• Original: J:302865 Le PT, et al., The role of Zfp467 in mediating the pro-osteogenic and anti-adipogenic effects on bone and bone marrow niche. Bone. 2021 Mar;144:115832
• All: 1 reference(s)