Pdk3^em1Eze
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pdk3^em1Eze
• Name: pyruvate dehydrogenase kinase, isoenzyme 3; endonuclease-mediated mutation 1, Elazar Zelzer
• MGI ID: MGI:6711988
• Gene: Pdk3 Location: ChrX:92808213-92875807 bp, - strand Genetic Position: ChrX, 41.34 cM
• Alliance: Pdk3^em1Eze page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 560 bp. (J:303714)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdk3 Mutation: 8 strains or lines available

References

• Original: J:303714 Heinemann-Yerushalmi L, et al., BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development. Dev Cell. 2021 Mar 23
• All: 2 reference(s)