B2m^b
Spontaneous Allele Detail

Summary

• Symbol: B2m^b
• Name: beta-2 microglobulin; b variant
• MGI ID: MGI:6711994
• Gene: B2m Location: Chr2:121978168-121983563 bp, + strand Genetic Position: Chr2, 60.55 cM, cytoband F1-F3
• Alliance: B2m^b page

Mutation origin

• Strain of Origin: C57BL

Mutation description

• Allele Type: Spontaneous (Not Applicable)
• Mutation: Nucleotide substitutions
• Mutation details: The b variant is runs faster than the a variant on SDS PAGE and was found to have an alanine at amino acid position 85. This allele is found in the C57BL strain family including C57BL/6, C57BL/10, C57L/J, C57BR/cdJ, as well as CAST/Ei, but not in C58/J, which has the a variant. (J:6520, J:7014)
• Inheritance: Codominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 6 strains available Cell Lines: 0 lines available
• Carrying any B2m Mutation: 122 strains or lines available

References

• Original: J:7014 Michaelson J, Genetics of beta-2 microglobulin in the mouse. Immunogenetics. 1983;17(3):219-60
• All: 15 reference(s)