Ikbip^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ikbip^em1Bcgen
• Name: IKBKB interacting protein; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:6712194
• Synonyms: IKIP^fl
• Gene: Ikbip Location: Chr10:90918802-90938469 bp, + strand Genetic Position: Chr10, 45.54 cM, cytoband C2
• Alliance: Ikbip^em1Bcgen page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9 mediated recombination introduced loxP sites around exon 2. (J:282971)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ikbip Mutation: 19 strains or lines available

References

• Original: J:282971 Wu H, et al., IKIP Negatively Regulates NF-kappaB Activation and Inflammation through Inhibition of IKKalpha/beta Phosphorylation. J Immunol. 2020 Jan 15;204(2):418-427
• All: 1 reference(s)