Sdcbp^tm1.1Zimmy
Targeted Allele Detail

Summary

• Symbol: Sdcbp^tm1.1Zimmy
• Name: syndecan binding protein; targeted mutation 1.1, Pascale Zimmermann
• MGI ID: MGI:6712409
• Gene: Sdcbp Location: Chr4:6365713-6396120 bp, + strand Genetic Position: Chr4, 2.91 cM, cytoband A1
• Alliance: Sdcbp^tm1.1Zimmy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:303742
• Parent Cell Line: iTL1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked hygromycin resistance cassette with a 5' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed exon 2 and left the FRT-flanked selection cassette intact. (J:303742)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sdcbp Mutation: 27 strains or lines available

References

• Original: J:303742 Kashyap R, et al., Syntenin-knock out reduces exosome turnover and viral transduction. Sci Rep. 2021 Feb 18;11(1):4083
• All: 2 reference(s)