Tg(Neurog1-cre/ERT2)G1CTahi
Transgene Detail

Summary

• Symbol: Tg(Neurog1-cre/ERT2)G1CTahi
• Name: transgene insertion G1C, Tatsumi Hirata
• MGI ID: MGI:6712707
• Synonyms: Neurog1^CreER(G1C)
• Transgene: Tg(Neurog1-cre/ERT2)G1CTahi Location: unknown
• Alliance: Tg(Neurog1-cre/ERT2)G1CTahi page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Neurog1-cre/ERT2)G1CTahi expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Neurog1 (MGI:107754)

• Mutation details: The transgene was constructed using a genomic BAC clone RP24-347K19 encoding the mouse neurogenin (Neurog)1 gene by replacing the entire coding sequence in exon1 with a CreERT2 cassette and the loxP site in the vector backbone (pTARBAC) was deleted by replacement with the zeocin resistance gene. The eleven mouse lines that independently received the transgene integration were then assayed for the Cre recombinase activities. Through this screen, one line (G1C) was selected by the highest recombination rate. (J:306016)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Neurog1 (mouse) Summary of all recombinase alleles driven by Neurog1. Alliance mouse Neurog1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:306016 Hirata T, et al., NeuroGT: A brain atlas of neurogenic tagging CreER drivers for birthdate-based classification and manipulation of mouse neurons. Cell Rep Med. 2021 Jul
• All: 1 reference(s)