Tg(Neurod1-cre/ERT2)D1BTahi
Transgene Detail

Summary

• Symbol: Tg(Neurod1-cre/ERT2)D1BTahi
• Name: transgene insertion D1B, Tatsumi Hirata
• MGI ID: MGI:6712709
• Synonyms: Neurod1^CreER(D1B)
• Transgene: Tg(Neurod1-cre/ERT2)D1BTahi Location: unknown
• Alliance: Tg(Neurod1-cre/ERT2)D1BTahi page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Neurod1-cre/ERT2)D1BTahi expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Neurod1 (MGI:1339708)

• Mutation details: The transgene was constructed using a genomic BAC clone RP23-280C11 encoding the mouse neurod1 gene by inserting a CreERT2 cassette at the first ATG sequence of exon2. The two mouse lines that independently received the transgene integration were then assayed for the Cre recombinase activities. Through this screen, one line (D1B) was selected by the highest recombination rate. (J:306016)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Neurod1 (mouse) Summary of all recombinase alleles driven by Neurod1. Alliance mouse Neurod1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:306016 Hirata T, et al., NeuroGT: A brain atlas of neurogenic tagging CreER drivers for birthdate-based classification and manipulation of mouse neurons. Cell Rep Med. 2021 Jul
• All: 1 reference(s)