Baiap2l2^em1Pgg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Baiap2l2^em1Pgg
• Name: BAI1-associated protein 2-like 2; endonuclease-mediated mutation 1, Peter G Gillespie
• MGI ID: MGI:6714004
• Synonyms: Baiap2l2^delta16
• Gene: Baiap2l2 Location: Chr15:79142395-79169737 bp, - strand Genetic Position: Chr15, 37.7 cM
• Alliance: Baiap2l2^em1Pgg page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of exon 4 deleted 16 bp resulting in an out of frame mutation (c.247_262delCGGCACTTGAACTCAG, p.Arg83ThrfsTer67). (J:305454)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Baiap2l2 Mutation: 22 strains or lines available

References

• Original: J:305454 Carlton AJ, et al., Loss of Baiap2l2 destabilizes the transducing stereocilia of cochlear hair cells and leads to deafness. J Physiol. 2021 Feb;599(4):1173-1198
• All: 1 reference(s)