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Ccr1l1em2Semp
Endonuclease-mediated Allele Detail
Summary
Symbol: Ccr1l1em2Semp
Name: C-C motif chemokine receptor 1 like 1; endonuclease-mediated mutation 2, Sergio M Pontejo
MGI ID: MGI:6714048
Synonyms: Ccr1l1-
Gene: Ccr1l1  Location: Chr9:123777280-123778445 bp, - strand  Genetic Position: Chr9, 75.05 cM, cytoband F
Alliance: Ccr1l1em2Semp page
Mutation
origin
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsUpstream of the locus and exon 1 were targeted with two sgRNAs (targeting GCTTTGCTATTAAACACGTAGGG and GGTATCTATCAATCGTAAGCAGG) using CRISPR/Cas9 technology, resulting in a 489 bp deletion that includes the start codon. (J:304824)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccr1l1 Mutation:  11 strains or lines available
References
Original:  J:304824 Kline JM, et al., Structural and functional analysis of Ccr1l1, a Rodentia-restricted eosinophil-selective chemokine receptor homologue. J Biol Chem. 2021 Feb 3;:100373
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory