Becn1^tm1Smoc
Targeted Allele Detail

Summary

• Symbol: Becn1^tm1Smoc
• Name: beclin 1, autophagy related; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6715552
• Synonyms: Becn1^fl
• Gene: Becn1 Location: Chr11:101179084-101193112 bp, - strand Genetic Position: Chr11, 64.58 cM, cytoband D
• Alliance: Becn1^tm1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306129
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 3 was flanked by loxP sites. (J:306129)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Becn1 Mutation: 36 strains or lines available

References

• Original: J:306129 Wang A, et al., ZFP91 is required for the maintenance of regulatory T cell homeostasis and function. J Exp Med. 2021 Feb 1;218(2)
• All: 1 reference(s)