Prss58^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prss58^em1Osb
• Name: serine protease 58; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6717357
• Gene: Prss58 Location: Chr6:40872204-40877321 bp, - strand Genetic Position: Chr6, 18.94 cM
• Alliance: Prss58^em1Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296968
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 2,501 bp. (J:296968)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Prss58 Mutation: 21 strains or lines available

References

• Original: J:296968 Park S, et al., CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity. Biol Reprod. 2020 Aug 4;103(2):195-204
• All: 1 reference(s)