Sppl2c^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sppl2c^em1Osb
• Name: signal peptide peptidase 2C; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6717376
• Gene: Sppl2c Location: Chr11:104077153-104081989 bp, + strand Genetic Position: Chr11, 67.79 cM
• Alliance: Sppl2c^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 4,295 bp. (J:296968)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Sppl2c Mutation: 35 strains or lines available

References

• Original: J:296968 Park S, et al., CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity. Biol Reprod. 2020 Aug 4;103(2):195-204
• All: 1 reference(s)