Trim10^em2Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim10^em2Cya
• Name: tripartite motif-containing 10; endonuclease-mediated mutation 2, Cyagen Biosciences
• MGI ID: MGI:6717383
• Synonyms: Trim10^em2Cgen
• Gene: Trim10 Location: Chr17:37180466-37188725 bp, + strand Genetic Position: Chr17, 19.16 cM
• Alliance: Trim10^em2Cya page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• TALEN-mediated genome-editing targeted exon 1 for deletion. (J:306658)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim10 Mutation: 27 strains or lines available

References

• Original: J:306658 Yang H, et al., Tripartite motif 10 regulates cardiac hypertrophy by targeting the PTEN/AKT pathway. J Cell Mol Med. 2020 Jun;24(11):6233-6241
• All: 1 reference(s)