Tg(ARR2/Pbsn-icre)58Atai
Transgene Detail

Summary

• Symbol: Tg(ARR2/Pbsn-icre)58Atai
• Name: transgene insertion 58, Atsu Aiba
• MGI ID: MGI:6718258
• Synonyms: PB-iCre58
• Transgene: Tg(ARR2/Pbsn-icre)58Atai Location: unknown
• Alliance: Tg(ARR2/Pbsn-icre)58Atai page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(ARR2/Pbsn-icre)58Atai expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pbsn (MGI:1860484)

• Mutation details: An improved cre (icre) gene was inserted downstream of the prostate-specific composite promoter that consists of two androgen response elements (ARR2) and mouse probasin (Pbsn) promoter. A total of 94 founders was generated. Line 58 with the detectable icre mRNA expression by RTPCR in the prostate was kept for further analyses. The expression of icre was mostly limited to the prostate gland with a trace expression in the seminal vesicle. (J:304912)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pbsn (mouse) Summary of all recombinase alleles driven by Pbsn. Comparative matrix view of recombinase activities Alliance mouse Pbsn gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:304912 Kanayama M, et al., Generation of transgenic mouse line with prostate-specific expression of codon-improved Cre recombinase. Prostate Int. 2018 Sep;6(3):99-103
• All: 1 reference(s)