Cd81^{em1(cre/ERT2)Kajim}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cd81^{em1(cre/ERT2)Kajim}
• Name: CD81 antigen; endonuclease-mediated mutation 1, Shingo Kajimura
• MGI ID: MGI:6718376
• Synonyms: Cd81-Cre^ERT2
• Gene: Cd81 Location: Chr7:142606487-142621667 bp, + strand Genetic Position: Chr7, 88.1 cM
• Alliance: Cd81^{em1(cre/ERT2)Kajim} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Cd81^{em1(cre/ERT2)Kajim} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cd81 (MGI:1096398)

• Mutation details: CRISPR/Cas9 genome editing technology was used to insert an ERT2 expression cassette into the CD81 gene locus. (J:304738)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cd81 (mouse) Summary of all recombinase alleles driven by Cd81. Comparative matrix view of recombinase activities Alliance mouse Cd81 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd81 Mutation: 22 strains or lines available

References

• Original: J:304738 Oguri Y, et al., CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling. Cell. 2020 Aug 6;182(3):563-577.e20
• All: 2 reference(s)