Dzip1^tm1Sasl
Targeted Allele Detail

Summary

• Symbol: Dzip1^tm1Sasl
• Name: DAZ interacting protein 1; targeted mutation 1, Susan Slaugenhaupt
• MGI ID: MGI:6718491
• Gene: Dzip1 Location: Chr14:119112932-119162872 bp, - strand Genetic Position: Chr14, 62.56 cM, cytoband E4
• Alliance: Dzip1^tm1Sasl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:291454
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The targeting vector (PG00125_Z_2_E04) introduced into intron 7 an FRT site, splice acceptor, lacZ reporter gene, loxP site, neomycin resistance cassette, FRT site and loxP site. An additional loxP site was inserted downstream of exon 8. (J:291454)

Disease models

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dzip1 Mutation: 38 strains or lines available

References

• Original: J:291454 Toomer KA, et al., Primary cilia defects causing mitral valve prolapse. Sci Transl Med. 2019 May 22;11(493)
• All: 3 reference(s)