Tg(Islr-cre/ERT2)#Tobe
Transgene Detail

Summary

• Symbol: Tg(Islr-cre/ERT2)#Tobe
• Name: transgene insertion, Kazuyuki Tobe
• MGI ID: MGI:6718533
• Synonyms: Meflin-CreER^T2
• Transgene: Tg(Islr-cre/ERT2)#Tobe Location: unknown
• Alliance: Tg(Islr-cre/ERT2)#Tobe page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Islr-cre/ERT2)#Tobe expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Islr (MGI:1349645)

• Mutation details: CAG-cre/ERT2 was inserted at the translational initiation Met of the mouse Islr (Meflin) gene in a bacterial artificial chromosome (BAC) genomic clone (B6Ng01-165L10) using recombineering. 4 founders were generated, but line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:304399)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Islr (mouse) Summary of all recombinase alleles driven by Islr. Comparative matrix view of recombinase activities Alliance mouse Islr gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:304399 Kuwano T, et al., Generation and characterization of a Meflin-CreERT2 transgenic line for lineage tracing in white adipose tissue. PLoS One. 2021;16(3):e0248267
• All: 1 reference(s)