Tg(Ghrl-cre)E7Jmz
Transgene Detail

Summary

• Symbol: Tg(Ghrl-cre)E7Jmz
• Name: transgene insertion E7, Jeffrey M Zigman
• MGI ID: MGI:6718600
• Synonyms: Ghrelin-Cre
• Transgene: Tg(Ghrl-cre)E7Jmz Location: unknown
• Alliance: Tg(Ghrl-cre)E7Jmz page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Ghrl-cre)E7Jmz expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ghrl (MGI:1930008)

• Mutation details: A bacterial artificial chromosome (BAC: RP23-128E5) containing nearly 192.04 kb sequence upstream of the mouse Ghrl start codon and nearly the entire coding sequence of the gene, ending ~1.17 kb upstream of the stop codon was modified by inserting a cre sequence into the translational start site of the gene removing the first 29bp of the coding sequence. Multiple lines were made and one line named E7 was used for the studies. (J:303659)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ghrl (mouse) Summary of all recombinase alleles driven by Ghrl. Comparative matrix view of recombinase activities Alliance mouse Ghrl gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:303659 Engelstoft MS, et al., Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells. Mol Metab. 2013;2(4):376-92
• All: 5 reference(s)