Tmem150c^em1(cre)Uoh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmem150c^em1(cre)Uoh
• Name: transmembrane protein 150C; endonuclease-mediated mutation 1, Uhtaek Oh
• MGI ID: MGI:6718970
• Synonyms: Ttn3^Cre
• Gene: Tmem150c Location: Chr5:100225731-100307667 bp, - strand Genetic Position: Chr5, 48.46 cM
• Alliance: Tmem150c^em1(cre)Uoh page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Tmem150c^em1(cre)Uoh expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tmem150c (MGI:3041258)

• Mutation details: Using the CRISPR/Cas9 system, cre recombinase gene followed by the SV-40 polyA signal sequence was inserted at the start codon of the mouse Tmem150c gene. (J:301989)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tmem150c (mouse) Summary of all recombinase alleles driven by Tmem150c. Comparative matrix view of recombinase activities Alliance mouse Tmem150c gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem150c Mutation: 19 strains or lines available

References

• Original: J:301989 Lu HJ, et al., Tentonin 3/TMEM150C senses blood pressure changes in the aortic arch. J Clin Invest. 2020 Jul 1;130(7):3671-3683
• All: 1 reference(s)