Rab26^em1Guwa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rab26^em1Guwa
• Name: RAB26, member RAS oncogene family; endonuclease-mediated mutation 1, Guansong Wang
• MGI ID: MGI:6719236
• Gene: Rab26 Location: Chr17:24748038-24752696 bp, - strand Genetic Position: Chr17, 12.4 cM
• Alliance: Rab26^em1Guwa page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: TALEN-mediated gene targeting generated a 2 bp deletion in exon 1. Western blot analysis confirmed absence of expression in the lungs. (J:306921)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rab26 Mutation: 17 strains or lines available

References

• Original: J:306921 Dong W, et al., RAB26-dependent autophagy protects adherens junctional integrity in acute lung injury. Autophagy. 2018;14(10):1677-1692
• All: 1 reference(s)