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Rab26em1Guwa
Endonuclease-mediated Allele Detail
Summary
Symbol: Rab26em1Guwa
Name: RAB26, member RAS oncogene family; endonuclease-mediated mutation 1, Guansong Wang
MGI ID: MGI:6719236
Gene: Rab26  Location: Chr17:24748038-24752696 bp, - strand  Genetic Position: Chr17, 12.4 cM
Alliance: Rab26em1Guwa page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsTALEN-mediated gene targeting generated a 2 bp deletion in exon 1. Western blot analysis confirmed absence of expression in the lungs. (J:306921)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rab26 Mutation:  17 strains or lines available
References
Original:  J:306921 Dong W, et al., RAB26-dependent autophagy protects adherens junctional integrity in acute lung injury. Autophagy. 2018;14(10):1677-1692
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory